St. Francis Inter College was established in July 1972 by Most Rev. Fr. Dr. Dominic Athaide O. F. M. Cap. then Archbishop of Agra in a rented building. It had a humble beginning with 20 students and 3 classrooms. Rev. Fr. Jose Maliekal was the founding Principal. In 1973 Mission Sisters of Ajmer jointed Hathras Mission at the invitation of the Archbishop. They continue to render their valuable service for the growth and development of the Institution and Hathras at large. In 1983 Rev. Fr. Thomas K. K then principal shifted the school from Munni Lal Ki Bagichi, Agra Road, Hathras to the present campus. The first batch of class X passed out of the institution in 1986. The first batch of class XII appeared for the Board Examination in March 1994. With the blessing and laying down the foundation stone for the Jesu Christi Jayanti 2000 Jubilee wing(present senior wing) by Rev. Fr. Jose Maliekal on 6th February 2005 the institution has an extended campus.